76469-88-0, name is Methyl 4-(cyanomethyl)benzoate, belongs to nitriles-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. name: Methyl 4-(cyanomethyl)benzoate
j00372j To a solution of product from Step 2 (200 mg, 0.695 mmol) in methanol (30 mL) were added methyl 4-(cyanomethyl)benzoate (0.83 4 mmol) and NaOH (1.39 mmol). The resulting mixture was stirred at 50C for 4h. After the reaction mixture was cooled, it was diluted with THF (20 mL) then stirred at room temperature for 10 minutes. The solids were isolated by filtration to provide the title compound (202 mg, 65%) as a yellow solid. LCMS [M+H]: 444.9.
The synthetic route of 76469-88-0 has been constantly updated, and we look forward to future research findings.