Synthetic Route of 5414-21-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 5414-21-1, name is 5-Bromovaleronitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
To a solution of 5-bromovaleronitrile (5.12 g, 30.0 mmol) in DMF (40 mL) was added potassium phthalimide (6.00 g, 32.4 mmol). The above suspension was heated at 60 oC for 16 h, concentrated, and partitioned between H20 and DCM. The DCM layer was separated, washed with HA0 (3x) and brine, dried over NA2S04, and concentrated to give the title compound (6.84 g, quantitative yield) as a white solid. 1H NMR (CDC13) : delta 7.87-7. 80 (m, 2H), 7.76-7. 70 (m, 2H), 3.73 (t, 2H, J= 6. 1HZ), 2.43 (t, 2H, J= 7.1 Hz), 1.89-1. 82 (m, 2H), 1.74-1. 67 (m, 2H).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Bromovaleronitrile, other downstream synthetic routes, hurry up and to see.