In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 1187-42-4 as follows. HPLC of Formula: C4H4N4
General procedure: To a mixture of 2,3-diaminomaleonitrile (1 mmol) and corresponding aromatic aldehyde (1 mmol) in H2O (5 mL), cerium (IV) ammonium nitrate (5 molpercent) was added and the reaction mixture stirred at room temperature for the desired time, as shown in Table 3. After completion of the reaction (reaction progress was monitored by TLC, ethyl acetate/n-hexane, 3:1), cold water (5?10 mL) was addedand the solid was filtered and washed with cold water/ethanol and air-dried to give the Schiff base product.
According to the analysis of related databases, 1187-42-4, the application of this compound in the production field has become more and more popular.