Application of 214623-57-1, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 214623-57-1, name is 5-Amino-2-methoxybenzonitrile, This compound has unique chemical properties. The synthetic route is as follows.
Sodium nitrite (l.llg, 16.17 mmol) in water (5 ml) was added with stirring over 15 min to a cold (0 C) solution of A (2.18 g,14.7 mmol) in concentrated hydrochloric acid (7 ml) and ice (10 g). The mixture was stirred at 0 C for a further 20 min. and the cold solution was added over 30 min to a stirred solution (room temperature) of potassium iodide (12.2 g, 73 mmol) in water (15 ml). The mixture was left standing at room temperature overnight and extracted with dichlormethane (2×50 ml). The combined organic extracts were washed successively with 10% NaOH, water, and dried (Na2S04). Evaporation of the solvent and silica gel column chromatography of the residue (Hexanes/EtOAc) gave iodide B (3.46 g, 80%).
The chemical industry reduces the impact on the environment during synthesis 5-Amino-2-methoxybenzonitrile. I believe this compound will play a more active role in future production and life.