Continuously updated synthesis method about 4-Amino-3,5-dichlorobenzonitrile

According to the analysis of related databases, 78473-00-4, the application of this compound in the production field has become more and more popular.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 78473-00-4, name is 4-Amino-3,5-dichlorobenzonitrile, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 4-Amino-3,5-dichlorobenzonitrile

To a solution of 4-amino-3,5-dichlorobenzonitrile (2.00 g, 10.63 mmol) in acetonitrile (12 ml) was added dropwise tetrafluoroboric acid (2.80 ml, 21.27 mmol). After stirring for 10 min, isoamyl nitrite (1.50 ml, 10.63 mmol) was added and the reaction mixture was cooled to 0 C. After a further 10 min, diethyl ether (50 ml) was added and the resulting precipitate was collected by filtration and dried to give the titled compound (1.9 g). 1H-NMR (D2O): 8.36-8.40 (2H)

According to the analysis of related databases, 78473-00-4, the application of this compound in the production field has become more and more popular.