Analyzing the synthesis route of 3-Oxopentanenitrile

According to the analysis of related databases, 33279-01-5, the application of this compound in the production field has become more and more popular.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 33279-01-5, name is 3-Oxopentanenitrile, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of 3-Oxopentanenitrile

A solution of 3-oxo-pentanenitrile (1.582 g, 16.49mmol), ethylene glycol (1.026 ml, 84. 59 mmol) and a catalytic amount of p-Toluene sulphonic acid (8 mg) in Toluene (10 ml) is refluxed at 150OC for 2 days using Dean-Stark apparatus. The reaction mixture is diluted with ethyl acetate and washed with saturated sodium bicarbonate solution. The organic phase is dried over MGS04, filtered, and the solvent evaporated to yield (2-ETHYL- [1, 3] dioxolan-2-yl)- acetonitrile. 1H NMR (400MHZ, CDC13) d 4.15 (2H, m), 4.05 (2H, m), 2.65 (2H, s), 1. 80 (2H, q), 0.95 (3H, t)

According to the analysis of related databases, 33279-01-5, the application of this compound in the production field has become more and more popular.