Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 35202-54-1, name is 4,5-Dimethoxy-1-cyanobenzocyclobutane, A new synthetic method of this compound is introduced below., SDS of cas: 35202-54-1
4,5-Dimethoxy-1-cyanobenzocyclobutane (10 g, 52.85 mmol)Soluble in ammonia-methanol solution (2M, 530ml), replacing nitrogen three times,Then add Raney nickel (1.0g)Replace hydrogen (45psi),The reaction was stirred at 20 °C for 12 h. TLC detection is complete, filtered through diatomaceous earth,The solvent was evaporated to give 4,5-dimethoxy-1-methylaminobenzocyclobutane (10.0 g, 98percent) as an oil.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.