Related Products of 13338-63-1,Some common heterocyclic compound, 13338-63-1, name is 3,4,5-Trimethoxyphenylacetonitrile, molecular formula is C11H13NO3, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: The solution of NaOH (2.71g, 67.93mmol) in water (20mL) was added at room temperature to the solution of polymethoxyphenylacetonitrile [40] (5.0g, 33.96mmol) and hydroxylamine hydrochloride (4.72g, 67.93mmol) in EtOH (100mL). The reaction mixture was refluxed for 5h, the solvent was evaporated in vacuo, and the residue was washed by water (3×30mL) and dried. Yield 75-80%.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 3,4,5-Trimethoxyphenylacetonitrile, its application will become more common.