Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 29509-06-6, name is 4-Methyl-3-oxopentanenitrile, A new synthetic method of this compound is introduced below., Application In Synthesis of 4-Methyl-3-oxopentanenitrile
EXAMPLE 58 Preparation of 1-methyl-3-(1-methylethyl)-5(1H)-pyrazolamine 4-Methyl-3-oxo-pentanenitrile (39.58 g; 0,356 mol) dissolved in glacial acetic acid (400 ml) and methylhydrazine (18.05 g; 0.382 mol) is added thereto, at 15-20 C. The reaction mixture is heated to 70-75 C. under nitrogen stream for about 5 hours. Then the mixture is cooled, and the solvent is evaporated under reduced pressure. The residue is taken up with water (200 ml) and the pH adjusted to about 9. After extraction with methylene chloride, the solvent of the dried organic layer is stripped off. The residue is taken up in ethyl ether and recovered by filtration. M.p. 115-118 C.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Gruppo Lepetit S.p.A.; US4954508; (1990); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts