Application of 622-75-3, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 622-75-3, name is 2,2′-(1,4-Phenylene)diacetonitrile, This compound has unique chemical properties. The synthetic route is as follows.
1,4-Benzene diacetonitrile solid (0.312 g, 2 mmol) and pyridine-4-carbaldehyde liquid (0.45 mL, 4.4 mmol) were added to a round bottom flask containing dichloromethane (40 mL). When the solid is completely dissolved, the solution is brownish yellow. The mixture was heated and stirred at 50 C in a water bath, and 0.45 mL of tetrabutylammonium hydroxide (TBAH, 40% methanol solution) was added by a syringe, and the solution was changed from brownish yellow to dark green. The reaction was stirred with a water bath at 50 C for 2 h, and TLC showed the reaction was completed. The solvent was evaporated to dryness with a rotary evaporator, and the solid was washed with water, filtered, and filtered, and then filtered, and then filtered and washed with EtOAc. The solid was 0.49 g. The yield was 73.5%.
The chemical industry reduces the impact on the environment during synthesis 2,2′-(1,4-Phenylene)diacetonitrile. I believe this compound will play a more active role in future production and life.