Application of 3759-28-2, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3759-28-2, name is 2-(Cyanomethyl)benzonitrile, This compound has unique chemical properties. The synthetic route is as follows.
Sodium hydride (60%, 12.0g, 0.3mol) was added to tetrahydrofuran (150mL), cooled to 0 degrees in an ice water bath, and a solution of compound 18 (14.2g, 0.1mol) in tetrahydrofuran (50mL) was added dropwise. Stir for 1 hour. The reaction solution was cooled again to 0 degrees, CH3I (57.0g, 0.4mol) was added dropwise, stirred at room temperature overnight, poured into ice water (200mL) to quench, extracted with ethyl acetate (50mL x 2), the organic phase was dried over sodium sulfate concentrate. Methyl tert-butyl ether (20 mL) and petroleum ether (50 mL) were added, filtered with stirring, and dried in vacuo to give compound 19 as a yellow solid (13.8 g, yield 18.1%).
The chemical industry reduces the impact on the environment during synthesis 2-(Cyanomethyl)benzonitrile. I believe this compound will play a more active role in future production and life.