Synthetic Route of 916792-13-7, These common heterocyclic compound, 916792-13-7, name is 4-Bromo-2-fluoro-5-methylbenzonitrile, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: The requisite aryl boronate derivative was prepared from the corresponding aryl bromide via reaction with 4,4,4′,4′,5,5,5′,5′-octamethyl-2,2′-bi-l,3,2-dioxaborolane in the presence of [1,1′- bis(diphenylphosphino)ferrocene]dichloropalladium(l l) and potassium acetate.
The synthetic route of 916792-13-7 has been constantly updated, and we look forward to future research findings.