Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 591769-05-0, Name is 3-Cyclopentylacrylonitrile, molecular formula is C8H11N. In an article, author is Li, Zhenghua,once mentioned of 591769-05-0, Recommanded Product: 591769-05-0.
Enantioselective Cyanoborylation of Allenes by N-Heterocyclic Carbene-Copper Catalysts
The simultaneous incorporation of both a cyano group and a boryl unit into the C=C double bonds of allenes in a regio- and stereoselective fashion is of much interest and importance but remains a significant challenge. We report herein a copper-catalyzed chemo-, regio-, and enantioselective cyanoborylation of allenes, which afforded a family of valuable enantiopure beta-boryl allyl nitriles. The high enantioselectivity was achieved by installing of appropriate substituents at the C2 and C6 positions of the naphthyl groups in our newly synthesized N-heterocyclic carbene (NHC) ligands. The reaction mechanism has been clarified by some stoichiometric reactions and computational studies. This work provides an inspiring example of the development of selective catalytic reactions for the synthesis of functional molecules through fine-tuning the ligands in catalysis.
Interested yet? Keep reading other articles of 591769-05-0, you can contact me at any time and look forward to more communication. Recommanded Product: 591769-05-0.