Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 623-03-0, Name is 4-Chlorobenzonitrile, molecular formula is C7H4ClN. In an article, author is Fang, Wan-Yin,once mentioned of 623-03-0, Recommanded Product: 623-03-0.
Clickable Transformation of Nitriles (RCN) to Oxazolyl Sulfonyl Fluoride Warheads
The protocol for simple, efficient, and mild synthesis of oxazolyl sulfonyl fluorides was developed through Rh-2(OAc)(4)-catalyzed annulation of methyl-2-diazo-2-(fluorosulfonyl)acetate (MDF) or its ethyl ester derivative with nitriles. This practical method provides a general and direct route to a unique class of highly functionalized oxazolyl-decorated sulfonyl fluoride warheads with great potential in medicinal chemistry, chemical biology, and drug discovery.
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