Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 2920-38-9, Name is [1,1′-Biphenyl]-4-carbonitrile, molecular formula is C13H9N, belongs to nitriles-buliding-blocks compound, is a common compound. In a patnet, author is Wu, Jun, once mentioned the new application about 2920-38-9, Computed Properties of C13H9N.
Efficient construction of diverse 3-cyanoindoles under novel tandem catalysis
A novel and rapid construction of 3-cyanoindoles by palladium-catalyzed tandem reactions has been developed. N-H free unprotected, N-alkyl and N-aryl 3-cyanoindoles are obtained with good to excellent yields. The usefulness of this synthetic approach is further demonstrated by the successful synthesis of practical compounds such as the therapeutic estrogen receptor ligand A precursor. Mechanism study shows that the tandem catalysis exploits a Suzuki cross-coupling with subsequent base-induced isoxazole fragmentation, followed by the aldimine condensation.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 2920-38-9. The above is the message from the blog manager. Computed Properties of C13H9N.