Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 2920-38-9, Name is [1,1′-Biphenyl]-4-carbonitrile, molecular formula is C13H9N, belongs to nitriles-buliding-blocks compound. In a document, author is Gao, Jihui, introduce the new discover, Category: nitriles-buliding-blocks.
Nickel-Catalyzed Migratory Hydrocyanation of Internal Alkenes: Unexpected Diastereomeric-Ligand-Controlled Regiodivergence
A regiodivergent nickel-catalyzed hydrocyanation of a broad range of internal alkenes involving a chain-walking process is reported. When appropriate diastereomeric biaryl diphosphite ligands are applied, the same starting materials can be converted to either linear or branched nitriles with good yields and high regioselectivities. DFT calculations suggested that the catalyst architecture determines the regioselectivity by modulating electronic and steric interactions. In addition, moderate enantioselectivities were observed when branched nitriles were produced.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 2920-38-9. Category: nitriles-buliding-blocks.