Chemistry, like all the natural sciences, HPLC of Formula: C20H23FN2O2, begins with the direct observation of nature¡ª in this case, of matter.103146-25-4, Name is 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile, SMILES is N#CC1=CC=C(C(O)(C2=CC=C(F)C=C2)CCCN(C)C)C(CO)=C1, belongs to nitriles-buliding-blocks compound. In a document, author is Ahmad, Muhammad Siddique, introduce the new discover.
Cu-catalyzed cyanomethylation of imines and alpha,beta-alkenes with acetonitrile and its derivatives
We describe copper-catalyzed cyanomethylation of imines and alpha,beta-alkenes with a methylnitrile source and provide an efficient route to synthesize arylacrylonitriles and beta,gamma-unsaturated nitriles. This method tolerates aliphatic and aromatic alkenes substituted with a variety of functional groups such as F, Cl, Br, Me, OMe, tert-Bu, NO2, NH2 and CO2H with good to excellent yields (69-98%). These systems consist of inexpensive, simple copper catalyst and acetonitrile with its derivatives (alpha-bromo/alpha-iodo-acetonitrile) and are highly applicable in the industrial production of acrylonitriles.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 103146-25-4. HPLC of Formula: C20H23FN2O2.