Adding a certain compound to certain chemical reactions, such as: 6330-25-2, name is 2-Cyano-N-methyl-acetamide, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6330-25-2, Recommanded Product: 6330-25-2
General procedure: Sodium metal (46 mg, 2.0 mmol) was placed in a flask, equipped with reflux condenser and calcium chloride tube,and dissolved in absolute ethanol (4-5 ml). The obtained solution was treated with a mixture of the appropriate 3-carbamoylchromone 3 (1 mmol) and cyanoacetamide(2 mmol) and refluxed with stirring for 2 h. After coolingthe reaction mixture to room temperature, regardless of the presence of precipitate, the mixture was stirred and neutralized with 1 N HCl. The obtained fine crystalline precipitate was filtered off, washed with ethanol, dried, and recrystallized from a 1:3 mixture of DMF-EtOH.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Cyano-N-methyl-acetamide, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Kornev, Mikhail Yu.; Moshkin, Vladimir S.; Sosnovskikh, Vyacheslav Ya.; Chemistry of Heterocyclic Compounds; vol. 51; 7; (2015); p. 688 – 690; Khim. Geterotsikl. Soedin.; vol. 51; 7; (2015); p. 688 – 690,3;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts