Adding a certain compound to certain chemical reactions, such as: 21524-39-0, name is 2,3-Difluorobenzonitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 21524-39-0, Recommanded Product: 21524-39-0
EXAMPLE 13 6-Fluoro[1]benzothieno[2,3-b]pyrazine-2,3(lH,4H)-dione 2,3-difluorobenzonitrile (5.0 g, 35.9 mmol) was reacted with 3-mercaptopropionitrile and bromonitromethane following the procedure outlined in example 7 (Method K). Yield 4.72 g (62%) of 3-amino-2-nitro-7-fluorobenzo[b]thiophene. M.p. 238-40 C. 1 H-NMR (DMSO-d6): delta7.48-7.65 (m, 2H), 8.21 (d, 1H), 8.65-10.3 (br. s, 2H).
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Reference:
Patent; Novo Nordisk A/S; US5182279; (1993); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts