Related Products of 874-90-8, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 874-90-8, name is 4-Methoxybenzonitrile, This compound has unique chemical properties. The synthetic route is as follows.
General procedure: Aryl nitrile 4a-e (15.0mmol) was dissolved in ethanol (25mL) in a round-bottom two-necked balloon, under magnetic stirring, and hydroxylamine hydrochloride (2.085g, 30mmol) and aqueous NaOH (2 equiv, 10mL) were added to the mixture. The mixture was stirred at room temperature for 15-24h, monitoring the reaction by TLC. Then, the solvent was removed under rotary evaporation and water (20mL) was added to the crude mixture. The mixture was extracted with ethyl acetate (3¡Á20mL) and the organic layer was dried over anhydrous MgSO4 and filtered. The solvent was removed by rotary evaporation and the product was recrystallized from chloroform – hexane.
The chemical industry reduces the impact on the environment during synthesis 4-Methoxybenzonitrile. I believe this compound will play a more active role in future production and life.
Reference:
Article; Mayer, Joao C.P.; Sauer, Andre C.; Iglesias, Bernardo A.; Acunha, Thiago V.; Back, Davi F.; Rodrigues, Oscar E.D.; Dornelles, Luciano; Journal of Organometallic Chemistry; vol. 841; (2017); p. 1 – 11;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts