Application of 939-79-7

Statistics shows that 4-Methyl-3-nitrobenzonitrile is playing an increasingly important role. we look forward to future research findings about 939-79-7.

Application of 939-79-7, These common heterocyclic compound, 939-79-7, name is 4-Methyl-3-nitrobenzonitrile, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

A mixture of 4-methyl-3-nitrobenzontitrile (2.4Ig), 10% Pd on C ( ~lg) and ethanol was stirred under hydrogen. After 24 hours the reaction mixture was filtered through Celite, and the solvent reduced in vacuo and purified using flash chromatography to yield 3-amino-4-methyl-benzonitrile (1.2Ig).

Statistics shows that 4-Methyl-3-nitrobenzonitrile is playing an increasingly important role. we look forward to future research findings about 939-79-7.

Reference:
Patent; F. HOFFMANN-LA ROCHE AG; WO2009/93049; (2009); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts