Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 115279-57-7, name is 2-(4-Aminophenyl)-2-methylpropanenitrile, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 2-(4-Aminophenyl)-2-methylpropanenitrile
To a solution of compound 1 (4.3 g, 15 mmol) in acetic acid (100 mL) at 250C, was added 2-(4-aminophenyl)-2-methylpropanenitrile (2.4 g, 15 mmol). The reaction mixture was stirred at 250C for 30 mins. The reaction mixture was quenched with ice-water and the solid was filtered, washed with 10% cold aqueous NaHCtheta3 solution and cold water, and dried under vacuum to provide 14 (5.5 g, 89% ) as a yellowish solid. MS (m/z) (Nf +H): 411, 413; 1H-NMR (400Mz, DMSO-d, ppm) 10.13 (s, IH), 9.08 (s, IH), 8.72 (s, IH), 8.01 (d, IH, J=8.55Hz), 7.94 (d, IH, J=8.97Hz), 7.47 (d, 2H, J=8.55Hz), 7.14 (d, 2H, J=8.55Hz),1.68 (s, 6H).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 115279-57-7.
Reference:
Patent; PROGENICS PHARMACEUTICALS, INC.; WO2009/155527; (2009); A2;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts