Application of 612-24-8, The chemical industry reduces the impact on the environment during synthesis 612-24-8, name is 2-Nitrobenzonitrile, I believe this compound will play a more active role in future production and life.
General procedure: A mixture of benzonitriles (2a-p) (0.009 mol), sodium azide (0.009 mol) was dissolved in DIPEAc (5 ml) and allowed to stirr for 30 min at 80 FontWeight=”Bold” FontSize=”10″ C. After completion of the reaction (monitored by thin-layer chromatography, TLC), the reaction mixture was cooled to room temperature and poured on crushed ice. To it 5N HCl (10 mL) was added and stirred vigorously. Otained solid products was filtered and crystallized from ethanol. The synthesized compounds were confirmed by Melting points, IR, 1H and 13C NMR which were in good agreement with those reported in the literature.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Nitrobenzonitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Bhosle, Manisha R.; Shaikh, Dastgir S.; Khillare, Lalit D.; Deshmukh, Amarsinh R.; Mane, Ramrao A.; Synthetic Communications; vol. 47; 7; (2017); p. 695 – 703;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts