Application of 21524-39-0, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 21524-39-0 as follows.
Synthesis of 1-CyanophenothiazinePrepared 1-cyanophenothiazine as described in the literature starting from 2-aminobenzenethiol (2.1 mL, 2.46 g, 20 mmol), 2,3-difluorobenzonitrile (1.9 mL, 2.83 g, 20 mmol), and sodium hydride (1.09 g, 27.3 mmol) in 10 mL of DMF. After crystallizing from dichloromethane-ethanol, 1-cyanophenothiazine was obtaind as a dark yellow powder (1.34 g, 6 mmol, 30 C. yield).
According to the analysis of related databases, 21524-39-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Prosetta Antiviral, Inc.; US2012/238543; (2012); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts