Related Products of 90381-43-4,Some common heterocyclic compound, 90381-43-4, name is 7-Methoxy-2-naphthonitrile, molecular formula is C12H9NO, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
EXAMPLE 90C 7-Methoxy-8-nitro-2-naphthalenecarbonitrile Example 90B (3 g, 16.4 mmole) in acetic anhydride (30 mL) at 0 C. was treated with fuming HNO3 (1.2 mL), and the resulting thick slurry was diluted with water (20 mL), stirred 20 min then filtered and dried in vacuo to provide 3.69 g of the title compound as a yellow solid. MS (DCI/NH3) m/e 246 (M+NH4)+.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 7-Methoxy-2-naphthonitrile, its application will become more common.
Reference:
Patent; Abbott Laboratories; US6258822; (2001); B1;; ; Patent; Abbott Laboratories; US6284796; (2001); B1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts