Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 38487-85-3, name is 2-Amino-4-methoxybenzonitrile, A new synthetic method of this compound is introduced below., SDS of cas: 38487-85-3
General procedure: To the solution of anthranilonitrile S-1 (2.0 mmol) and Et3N (2.4 mmol) in 20 mL dry CH2Cl2 was added acryloyl chloride (2.2 mmol) at 0 C. The mixture was allowed to stir at room temperature. After completion of the reaction, the reaction was quenched with saturated NaHCO3 solution, then extracted with CH2Cl2, washed with brine, dried over MgSO4 and concentrated by evaporator affording amide S-2 without any further purification.
The synthetic route of 38487-85-3 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Yang, Tao; Zhou, Jia-Li; Li, Junpeng; Shen, Yuehai; Gao, Chuanzhu; Li, Ya-Min; Synthesis; vol. 50; 17; (2018); p. 3460 – 3466;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts