Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 71825-51-9, name is 2-Methyl-2-(4-nitrophenyl)propanenitrile, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 2-Methyl-2-(4-nitrophenyl)propanenitrile
16 g (84.1 mmol) of 2-methyl-2-(4-nitro-phenyl)-propionitrile (Example 1d) and 4.16 g of Raney-Ni are shacked in 160 ml of THF-MeOH (1 :1) under 1.1 bar of H2 for 12 h at rt. After completion of the reaction, the catalyst is filtered-off and the filtrate is evaporated to dryness. The residue is purified by flash chromatography on silica gel (hexane-EtOAc 3:1 to 1 :2) to provide the title compound as an oil. ES-MS: 161 (M + H)+; analytical HPLC: W= 2.13 minutes (Grad 1).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 71825-51-9.
Reference:
Patent; NOVARTIS AG; NOVARTIS PHARMA GMBH; WO2006/122806; (2006); A2;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts