Electric Literature of 25309-65-3,Some common heterocyclic compound, 25309-65-3, name is 4-Ethylbenzonitrile, molecular formula is C9H9N, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Step A. Methyl 4-ethylbenzenecarboximidoate Hydrodrochloride Hydrogen chloride gas was bubbled through a methanol solution of 4-ethylbenzonitrile (5.0 g, 38.11 mmol) at 0 C. for 30 minutes. The reaction was sealed and stood at ambient temperature overnight. The solvent was removed in vacuo and the oily residue triturated with diethyl ether. The resulting solid was removed to yield the title compound which was stored in a dry atmosphere.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 4-Ethylbenzonitrile, its application will become more common.
Reference:
Patent; American Home Products Corporation; US2002/22638; (2002); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts