These common heterocyclic compound, 1835-65-0, name is 3,4,5,6-Tetrafluorophthalonitrile, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. COA of Formula: C8F4N2
Example 20 CoPcF8 (PhO) 8 (SO3 H) 6 Synthesis example (4) of starting material CoPcF8 (Pho) 8 20.0 g (100 mmol) of tetrafluorophthalonitrile, 18.8 g (100 mmol) of phenol, 10.8 g of KF and 100 ml of acetonitrile were fed into a 200 ml of a four-necked flask, and the reaction mixture was stirred at 5¡ã C. for 3 hours. Thereafter, the solid matter was filtrated and the filtrate was evaporated for dryness. There was thus obtained 27.4 g of 3,6-difluoro-4,5-bisphenoxyphthalonitrile.
The synthetic route of 3,4,5,6-Tetrafluorophthalonitrile has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Nippon Shokubai Co., Ltd.; US5359056; (1994); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts