Electric Literature of 3672-47-7, A common heterocyclic compound, 3672-47-7, name is 3-(4-Methoxyphenyl)-3-oxopropanenitrile, molecular formula is C10H9NO2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: Fresh cells and lyophilised cells of Rhodotorula rubra MIM147 were used 20gL-1 dry weight re-suspended in phosphate buffer or in tap water with 50gL-1 of glucose; then the substrates 1, 3-10 were dissolved in DMSO and added at 2gL-1 concentration. For substrate 1, biotransformations were also carried out at 4, 6 or 10gL-1 concentration.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Rimoldi, Isabella; Facchetti, Giorgio; Nava, Donatella; Contente, Martina Letizia; Gandolfi, Raffella; Tetrahedron Asymmetry; vol. 27; 9-10; (2016); p. 389 – 396;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts