Electric Literature of 4107-65-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 4107-65-7, name is 2,4-Dimethoxybenzonitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Example 1 8-(2,4-Dimethoxy-phenyl)-purine A mixture of 2 g of 4,5-diamino-pyrimidine, 4 g of 2,4-dimethoxy-benzonitrile, 6 g of p-toluene sulfonic acid hydrate, and 40 ml of benzene was heated, whereby the benzene was distilled off. The residue was heated for 30 minutes at 120 C. After cooling the residue was triturated with 2 N ammonia and extracted with ethyl acetate. The ethyl acetate phase was extracted with 2 N hydrochloric acid, the aqueous phase was neutralized and again extracted with ethyl acetate, and subsequently the organic phase was extracted with 2 N sodium hydroxide solution. When the aqueous phase was neutralized, the product was precipitated and recrystallized from water. Yield: 0.15 g (3% of theory), M.P.: 221 C. (decomp).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2,4-Dimethoxybenzonitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Boehringer Ingelheim Gesellschaft mit beschrankter Haftung; US4299834; (1981); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts