The important role of 3672-47-7

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-(4-Methoxyphenyl)-3-oxopropanenitrile, other downstream synthetic routes, hurry up and to see.

Electric Literature of 3672-47-7, The chemical industry reduces the impact on the environment during synthesis 3672-47-7, name is 3-(4-Methoxyphenyl)-3-oxopropanenitrile, I believe this compound will play a more active role in future production and life.

To a stirred solution of 0.30 g (1.71 mmol) 3-(4-methoxy-phenyl)- 3-oxo-propionitrile in 10 ml ethanol was added 0.17 ml (1.71 mmol) cyclohexanone, 53 mg (1.71 mmol) sulfur, EPO and 0.14 ml (1.71 mmol) morpholine. The mixture was heated at 40 0C for the week end, and then poured onto water and extracted three times with ethyl acetate. The combined organic phases were dried over sodium sulfate and concentrated in vacuo. Trituration in ether afforded 0.51 g (85%) (2-amino-4,5,6,7-tetrahydro-benzo[b]thiophen-3-yl)-(4- methoxy-phenyl)-methanone as an orange solid. ES-MS m/e (%): 288 (M+H+, 100).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-(4-Methoxyphenyl)-3-oxopropanenitrile, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; F.HOFFMANN-LA ROCHE AG; WO2006/63732; (2006); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts