Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 4110-35-4, name is 3,5-Dinitrobenzonitrile, A new synthetic method of this compound is introduced below., Recommanded Product: 3,5-Dinitrobenzonitrile
Preparation 133 A suspension of 3,5-dinitrobenzonitrile (2.75g) in methanol (15ml) and tetrahydrofuran (15ml) was hydrogenated over 10 % palladium on carbon (50% wet) under hydrogen atmosphere for 6 hours. The catalyst was filtered off. The filtrate was concentrated, purified with silica gel column chromatography and eluted with dichloromethane in 0-1% methanol to give 3-cyano-5-nitroaniline (951mg). ESI-mass;m/z162.3(M-H+) 1H-NMR(DMSO-d6): delta;6.33(2H,s), 7.24(1H,s), 7.6-7.8(2H,m)
The synthetic route of 4110-35-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; FUJISAWA PHARMACEUTICAL CO., LTD.; EP1264820; (2002); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts