Electric Literature of 1129-35-7,Some common heterocyclic compound, 1129-35-7, name is Methyl 4-cyanobenzoate, molecular formula is C9H7NO2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
A mixture OF METHYL-4-CYANOBENZOATE (5.0 g, 0. 031 MOL) and diethyl dithiophosphate (11.5 g, 0.062 mol) in water (100 mL) was stirred overnight at 80C under a nitrogen atmosphere. The reaction mixture was allowed to cool to ambient temperatures and the solid was filtered and washed with water (100 mL). The solid was then dried in vacuo at 40C to give the crude product (4.74 g, 78%).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route Methyl 4-cyanobenzoate, its application will become more common.
Reference:
Patent; APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.; WO2005/11685; (2005); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts