Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 92616-49-4, name is 4-Bromo-1-naphthonitrile, A new synthetic method of this compound is introduced below., SDS of cas: 92616-49-4
19.5g (84mmol) 4-bromo-1-naphthonitrile, 5.88g (48mmol) hydroxylamine hydrochloride, 4.65g (84mmol) sodium methoxide in a methanol solvent paste has better mouth feeling and the reflux time 18. Reactants as ethyl acetate 10% sodium hydroxide aqueous solution 3 which has ethyl water insoluble chemical additives present after extracted times. Saline to which washes the 3 times during the drying process and magnesium sulfate anhydride, filtration, after concentrating dissolved back to solvent ethanol 16 doesn’t have any error frames, Raney nickel 2g the reflux time. Product to filter out removing the catalyst after concentrated within, silica gel chromatography (CHCl2/ethanol) purified after solid compound (10.0g) of 48% are obtained
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Choe, Don Soo; Jo, Yun Hwan; (92 pag.)KR2015/80966; (2015); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts