Introduction of a new synthetic route about 915394-28-4

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Methyl-2-(3-nitrophenyl)propanenitrile, other downstream synthetic routes, hurry up and to see.

Adding a certain compound to certain chemical reactions, such as: 915394-28-4, name is 2-Methyl-2-(3-nitrophenyl)propanenitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 915394-28-4, Application In Synthesis of 2-Methyl-2-(3-nitrophenyl)propanenitrile

2-Methyl-2-(3-nitrophenyl)-propionitrile (0.5g) was hydrogenated over 10% Pd-C in methanol (10ml) at atmospheric pressure until no further gas uptake was observed. The reaction mixture was then filtered over celite and concentrated to oil. Column chromatography over silica gel by eluting with ethyl acetate/pet ether (1:9) gave 2-(3- amino-phenyl)-2-methyl-propionitrile (0.35g, 83%) as an oil.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Methyl-2-(3-nitrophenyl)propanenitrile, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; F2G LTD; WO2006/123145; (2006); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts