Related Products of 628-20-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 628-20-6, name is 4-Chlorobutyronitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Under nitrogen protection, 0.5 L of tetrahydrofuran, 103.5 g (1 mol) of 4-chlorobutyronitrile, 2.52 g (0.02 mol) of anhydrous manganese chloride, 387 g (3 mol) of dimethyldichlorosilane,0.31 g of dibromoethane was added to the reactor, stirred and heated to 65 C.0.514g of magnesium turnings were added for the first time. After the reaction was initiated, 25.17g of magnesium turnings were added again for 2 hours. After the reaction was completed, the reaction product was subjected to solid-liquid separation, and the liquid phase was subjected to rectification, and the fraction was collected at a suitable temperature to obtain a cyano group. Organosilicon compound monomer (ie 3-cyanopropyldimethylchlorosilane). The yield of the obtained cyano group-containing organosilicon compound monomer was 96.1%, and the purity was 99.6%.
The synthetic route of 4-Chlorobutyronitrile has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Shandong Dongyue Silicone Materials Co., Ltd.; Yi Gang; Hu Qingchao; Wang Chunxiao; Liu Hailong; Guo Jianqiang; Li Yunjie; Sun Jiang; Xiao Yueling; (6 pag.)CN109879902; (2019); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts