Adding some certain compound to certain chemical reactions, such as: 40497-11-8, name is Ethyl 2,3-dicyanopropanoate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 40497-11-8. 40497-11-8
Ethyl 2,3-dicyanopropionate (1.0 mmol) was added to 20.0 ml of ethanol, vigorously stirred., then Hydrazine hydrate (2.0 mmol) was added to the reaction solution, and the mixture was heated under reflux for 3 hours. The heating was stopped and the mixture was cooled to room temperature. The mixture was concentrated in vacuo and the mixture was extracted with ethyl acetate and water. The resulting ethyl acetatewas extracted andconcentrated in vacuo to give 5-amino-1H-pyrazole-3-cyano as a white solid. The intermediate was used directly in the next step without further purification.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Ethyl 2,3-dicyanopropanoate.
Reference:
Patent; South China Agricultural University; Xu Hanhong; Jiang Xunyuan; Wei Xiaoyi; Zhang Zhixiang; Lin Fei; Yao Guangkai; Deng Chengju; (50 pag.)CN108003162; (2018); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts