622-75-3, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 622-75-3, name is 2,2′-(1,4-Phenylene)diacetonitrile, A new synthetic method of this compound is introduced below.
Add 4- (2-oxiranylmethoxy) benzaldehyde (0.01 mol, 1.78 g), terephthalonitrile (0.0045 mol, 0.7000 g), and 150 mL of ethanol to a 250-mL single-necked bottle, and stir for 10 minutes. After several minutes, solid potassium hydroxide (0.03 mol, 1.68 g) was added, and after 4 to 6 hours of reaction, the reaction was stopped.After the temperature of the reaction system was cooled to room temperature, the solid product was collected by suction filtration, washed with water and dried to obtain a crude product. The crude product was recrystallized from a mixed solvent of DMF and ethanol (V: V = 3: 1) to obtain a pure yellow product 1.95. g, yield 93%.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Xiangtan University; Zhang Hailiang; Tan Huiping; Yuan Yongjie; Yang Bohao; (15 pag.)CN110407772; (2019); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts