Adding a certain compound to certain chemical reactions, such as: 555-21-5, name is 4-Nitrophenylacetonitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 555-21-5, 555-21-5
VI 5-0 g (30 mmol) was taken,Dissolved in 25 ml of ethanol,8 g (150 mmol) NH4Cl,Dissolved in 40 ml of water,Was added to a three-necked flask,5. 05 g (90 mmol) of iron powder was added,Mechanical stirring,Reflux 2h.Filter in addition to iron powder,CH2CV washing filter cake,Extraction with CH2C12,Saturated sodium chloride,Dried over anhydrous sodium sulfate,filter,Evaporated to dryness 3. 86 g of solid,The yield was 97.5%
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Nitrophenylacetonitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Hefei Industrial Pharmaceutical Institute Co., Ltd.; China Pharmaceutical University; NANJING MEDICAL INDUSTRY MEDICAL TECHNOLOGY CO LTD;; Xu, Yungen; Liu, Wei; He, Guangwei; Yang, Yun; Bian, Xueguo; (9 pag.)CN103408501; (2016); B;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts