403-54-3, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 403-54-3, name is 3-Fluorobenzonitrile, This compound has unique chemical properties. The synthetic route is as follows.
General procedure: A mixture of 3-methylbenzonitrile (5 mmol), benzyl acetate (6mmol), and Fe(ClO4)3¡¤H2O (5 mol%) was placed in a round-bottomedflask. Then, the reaction mixture was heated at 80 C for5 h. After completion of the reaction monitored by thin layerchromatography (TLC), water (10 mL) was added, and the reactionmixture was extracted with ethyl acetate (3 ¡Á 20 mL). Theorganic layers were collected, combined, washed with water (3¡Á 20 mL), dried with anhydrous Na2SO4, and concentrated undervacuum. The pure product was obtained by directly passingthrough a silica gel (200-300 mesh) column to give a whitepowder n (0.96 g, 86% yield)..
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Reference:
Article; Feng, Chengliang; Yan, Bin; Yin, Guibo; Chen, Junqing; Ji, Min; Synlett; vol. 29; 17; (2018); p. 2257 – 2264;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts