63069-50-1, Name is 4-Amino-3-fluorobenzonitrile, 63069-50-1, belongs to nitriles-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows.
General procedure: To the solution of compound 15 (0.2 mmol) and 2-aminobenzonitrile (0.6 mmol) in n-BuOH (3 mL) was added DIPEA (0.6 mmol). After stirred at 90 C for 12 h, the reaction mixture was diluted with EtOAc, washed with brine, dried over MgSO4, and evaporated. The residue was purified by column chromatography to give the product 16 as yellow solid. (22 mg, 25%).
Statistics shows that 4-Amino-3-fluorobenzonitrile is playing an increasingly important role. we look forward to future research findings about 63069-50-1.
Reference:
Article; Fang, Yuanying; Yang, Zunhua; Gundeti, Shankariah; Lee, Jongkook; Park, Haeil; Bioorganic and Medicinal Chemistry; vol. 25; 1; (2017); p. 254 – 260;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts